The North End Police Station is a significant representative of the district police stations constructed to replace those lost in the 1906 fire.

It is a miniature example of San Francisco's monumental Academic civic architecture of the early 20th century, but its substyle is Spanish Colonial Revival rather than the Renaissance Revival employed at Civic Center. The designers included Frederick H. Meyer and John Reid, Jr., two of the three consulting architects responsible for the Civic Center Plan and the Civic Auditorium.

Its Academic Spanish Colonial Revival elements include the smooth walls, the ceramic tile roof, the arched entry, shaped side parapet, multi-level roofs, tapestry brick, and the wondertul spiky lanterns. The complementary rear building is also Academic style in a mixture of the Spanish Colonial Revival with Arts and Crafts substyles.

This was the district police station for the Panama Pacific International Exposition of 1915. It has been retired from service, replaced by the Northern Station on Fillmore Street.

From San Francisco Planning Commission Resolution 14066 adopted on March 7, 1996.