The Woodside Store is one of the earliest tangible remains of American settlement on the San Francisco Peninsula. The redwood board and batten structure is a notable example of its type and period and is one of the oldest such buildings in the state. It has a direct association with one of the area's important pioneers, Dr. Robert 0. Tripp, and served as a store, post office and center of local social and economic activity throughout much of its history.

The Woodside Store is also California Landmark 93.